Download E-books Sequence Alignment: Methods, Models, Concepts, and Strategies PDF

The sequencing of the human genome concerned hundreds of thousands of scientists yet used rather few instruments. at the present time, acquiring sequences is easier, yet aligning the sequences—making certain that sequences from one resource are accurately in comparison to these from different sources—remains a classy yet underappreciated point of comparative molecular biology. This quantity, the 1st to target this important step in examining series info, is ready the perform of alignment, the techniques wherein alignments are validated, and extra importantly, how the results of any alignment set of rules may be interpreted. Edited by way of Michael S. Rosenberg with essays through a few of the field's major specialists, Sequence Alignment covers molecular reasons, computational advances, techniques for assessing alignment caliber, and philosophical underpinnings of the algorithms themselves.

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